Implications of cleaved caspase 3 and AIF expression in colorectal cancer based on patient age

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Implications of cleaved caspase 3 and AIF expression in colorectal cancer based on patient age.

A high incidence of colorectal cancer (CRC) has been established in the elderly population. Apoptosis is a key event in maintaining colon homeostasis, both in aging as well as in cancer prevention. Here, we report that colon morphology is affected during the aging process: crypt loss (P=0.045) and increasing distances between crypts (P=0.0001678) were observed, associated with a tendency for mu...

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ژورنال

عنوان ژورنال: Oncology Reports

سال: 2012

ISSN: 1021-335X,1791-2431

DOI: 10.3892/or.2012.1737